mavorixafor will raise the stage or effect of codeine by influencing hepatic enzyme CYP2D6 metabolism. Contraindicated. Mavorixafor (a solid CYP2D6 inhibitor) is contraindicated with prescription drugs which might be highly dependent on CYP2D6 for clearance.Composition of Cough, The active compound is codeine phosphate hemihydrate. Just about ever